Computational Drug Repurposing Based on a Recommendation System and Drug-Drug Functional Pathway Similarity.

Shao, Mengting; Jiang, Leiming; Meng, Zhigang; Xu, Jianzhen

Shao, Mengting; Jiang, Leiming; Meng, Zhigang; Xu, Jianzhen.

Affiliation

Shao M; Computational Systems Biology Laboratory, Department of Bioinformatics, Shantou University Medical College (SUMC), Shantou 515041, China.
Jiang L; Department of Computer Science, College of Computer Engineering and Applied Mathematics, Changsha University, Changsha 410005, China.
Meng Z; Computational Systems Biology Laboratory, Department of Bioinformatics, Shantou University Medical College (SUMC), Shantou 515041, China.
Xu J; Department of Computer Science, College of Computer Engineering and Applied Mathematics, Changsha University, Changsha 410005, China.

Molecules ; 27(4)2022 Feb 18.

Article in En | MEDLINE | ID: mdl-35209193

Subject(s)

Computational Biology/methods; Drug Discovery/methods; Drug Repositioning/methods; Algorithms; Databases, Factual; Databases, Pharmaceutical; Genomics/methods; Humans; Precision Medicine/methods; Proteomics/methods; Structure-Activity Relationship; Workflow

Key words

drug functional similarity; drug repurposing; pathway activities; recommender system

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Computational Biology / Drug Discovery / Drug Repositioning Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: China

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