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Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.
Li, Derun; Sloman, David L; Achab, Abdelghani; Zhou, Hua; McGowan, Meredeth A; White, Catherine; Gibeau, Craig; Zhang, Hongjun; Pu, Qinglin; Bharathan, Indu; Hopkins, Brett; Liu, Kun; Ferguson, Heidi; Fradera, Xavier; Lesburg, Charles A; Martinot, Theodore A; Qi, Ji; Song, Zhiguo J; Yin, Jingjun; Zhang, Huangguang; Song, Licheng; Wan, Baoqiang; DAddio, Suzanne; Solban, Nicolas; Miller, J Richard; Zamlynny, Beata; Bass, Alan; Freeland, Elizabeth; Ykoruk, Bridget; Hilliard, Catherine; Ferraro, Jude; Zhai, Jin; Knemeyer, Ian; Otte, Karin M; Vincent, Stella; Sciammetta, Nunzio; Pasternak, Alexander; Bennett, David Jonathan; Han, Yongxin.
Affiliation
  • Zhang H; Pharmaron Beijing Co., Ltd., No.6 Taihe Road, Beijing 100176, China.
  • Song L; Pharmaron Beijing Co., Ltd., No.6 Taihe Road, Beijing 100176, China.
  • Wan B; WuXi AppTec Co., Ltd., No. 1 Building, #288 FuTe ZhongLu, WaiGaoQiao Free Trade Zone, Shanghai 100176, China.
J Med Chem ; 65(8): 6001-6016, 2022 04 28.
Article in En | MEDLINE | ID: mdl-35239336
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / Ethers, Cyclic Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / Ethers, Cyclic Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Type: Article