Into the unknown: Diagnosing mysterious brain lesions.
Transpl Infect Dis
; 24(4): e13829, 2022 Aug.
Article
in En
| MEDLINE
| ID: mdl-35307917
ABSTRACT
In this inaugural clinicopathological conference, the invited experts discussed the diagnostic approach to central nervous system infections in immunocompromised hosts. The case presented involved a pancreas-kidney transplant recipient with multiple brain abscesses caused by Bartonella henselae. CSF metagenomic next-generation sequencing played a significant role in the diagnosis. Bartonella henselae is a gram-negative zoonotic pathogen that causes cat-scratch disease, which can be transmitted to humans through cat bites or scratches. Symptoms can vary in severity, correlating with the patient's immune status. Visceral organ involvement, ocular involvement, and neurological manifestations have been reported in immunocompromised patients, but brain abscesses are rare.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cat-Scratch Disease
/
Bartonella henselae
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
Transpl Infect Dis
Journal subject:
TRANSPLANTE
Year:
2022
Type:
Article
Affiliation country:
United States