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Coronary Artery Disease and Aspirin Intolerance: Background and Insights on Current Management.
Thakker, Ravi A; Salazar, Leonardo; Jazar, Deaa Abu; Bhakta, Pooja; Baker, Bryan; Patel, Chandani; Elbadawi, Ayman; Agarwal, Mayank; Albaeni, Aiham; Saleh, Mohammed; Esclovan, Jonathan; El Haddad, Danielle; Alwash, Hashim; Kalra, Ankur; Goel, Sachin S; Widmer, Robert Jay; Chatila, Khaled; Khalife, Wissam; Motiwala, Afaq; McCracken, Jennifer; Jneid, Hani; Gilani, Syed.
Affiliation
  • Thakker RA; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA. ravi.a.thakker@gmail.com.
  • Salazar L; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Jazar DA; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Bhakta P; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Baker B; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Patel C; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Elbadawi A; Division of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Agarwal M; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Albaeni A; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Saleh M; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Esclovan J; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • El Haddad D; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Alwash H; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Kalra A; Division of Cardiovascular Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Goel SS; Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
  • Widmer RJ; Division of Cardiology, Scott and White Heart Memorial Hospital, Baylor Scott and White Health, Temple, TX, USA.
  • Chatila K; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Khalife W; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • Motiwala A; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
  • McCracken J; Division of Allergy and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
  • Jneid H; Division of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Gilani S; Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.
Cardiol Ther ; 11(2): 175-183, 2022 Jun.
Article in En | MEDLINE | ID: mdl-35344187
ABSTRACT
Aspirin is one of the most widely used medications across the global healthcare system and is the foundation in treating ischemic heart disease, as well as secondary prevention for ischemic and valvular heart disease. Challenges arise in treating patients with cardiovascular disease who have concomitant aspirin intolerance. Through an extensive review of the literature, we provide a comprehensive background on the pharmacology of aspirin, the mechanisms behind aspirin intolerance, the importance of aspirin in cardiovascular disease, and the management of aspirin intolerance in both acute coronary syndrome and stable coronary artery disease. Our review includes a multidisciplinary approach from the internist, allergist/immunologist, and cardiologist when evaluating this important patient population.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cardiol Ther Year: 2022 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cardiol Ther Year: 2022 Type: Article Affiliation country: United States