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FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira, Caroline; Crespo, Ângela; Ranjbar, Shahin; de Lacerda, Luna B; Lewandrowski, Mercedes; Ingber, Jacob; Parry, Blair; Ravid, Sagi; Clark, Sarah; Schrimpf, Marie Rose; Ho, Felicia; Beakes, Caroline; Margolin, Justin; Russell, Nicole; Kays, Kyle; Boucau, Julie; Das Adhikari, Upasana; Vora, Setu M; Leger, Valerie; Gehrke, Lee; Henderson, Lauren A; Janssen, Erin; Kwon, Douglas; Sander, Chris; Abraham, Jonathan; Goldberg, Marcia B; Wu, Hao; Mehta, Gautam; Bell, Steven; Goldfeld, Anne E; Filbin, Michael R; Lieberman, Judy.
Affiliation
  • Junqueira C; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. caroline.junqueira@childrens.harvard.edu.
  • Crespo Â; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. caroline.junqueira@childrens.harvard.edu.
  • Ranjbar S; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil. caroline.junqueira@childrens.harvard.edu.
  • de Lacerda LB; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Lewandrowski M; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Ingber J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Parry B; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Ravid S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Clark S; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Schrimpf MR; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
  • Ho F; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Beakes C; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Margolin J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Russell N; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Kays K; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA.
  • Boucau J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Das Adhikari U; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Vora SM; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Leger V; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Gehrke L; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Henderson LA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Janssen E; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Kwon D; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA.
  • Sander C; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA.
  • Abraham J; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA.
  • Goldberg MB; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA.
  • Wu H; Ragon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Cambridge, MA, USA.
  • Mehta G; Ragon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Cambridge, MA, USA.
  • Bell S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Goldfeld AE; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Filbin MR; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lieberman J; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Nature ; 606(7914): 576-584, 2022 06.
Article in En | MEDLINE | ID: mdl-35385861

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Receptors, IgG / SARS-CoV-2 / COVID-19 / Inflammation Limits: Humans Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Receptors, IgG / SARS-CoV-2 / COVID-19 / Inflammation Limits: Humans Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States