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Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth.
Cao, Minghui; Isaac, Roi; Yan, Wei; Ruan, Xianhui; Jiang, Li; Wan, Yuhao; Wang, Jessica; Wang, Emily; Caron, Christine; Neben, Steven; Drygin, Denis; Pizzo, Donald P; Wu, Xiwei; Liu, Xuxiang; Chin, Andrew R; Fong, Miranda Y; Gao, Ziting; Guo, Kaizhu; Fadare, Oluwole; Schwab, Richard B; Yuan, Yuan; Yost, Susan E; Mortimer, Joanne; Zhong, Wenwan; Ying, Wei; Bui, Jack D; Sears, Dorothy D; Olefsky, Jerrold M; Wang, Shizhen Emily.
Affiliation
  • Cao M; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Isaac R; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Yan W; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Ruan X; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Jiang L; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Wan Y; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Wang J; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Wang E; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Caron C; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Neben S; Regulus Therapeutics Inc., San Diego, CA, USA.
  • Drygin D; Regulus Therapeutics Inc., San Diego, CA, USA.
  • Pizzo DP; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Wu X; Department of Molecular and Cellular Biology, City of Hope, Duarte, CA, USA.
  • Liu X; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Chin AR; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Fong MY; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Gao Z; Department of Chemistry, University of California, Riverside, Riverside, CA, USA.
  • Guo K; Department of Chemistry, University of California, Riverside, Riverside, CA, USA.
  • Fadare O; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Schwab RB; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Yuan Y; Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA, USA.
  • Yost SE; Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA, USA.
  • Mortimer J; Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA, USA.
  • Zhong W; Department of Chemistry, University of California, Riverside, Riverside, CA, USA.
  • Ying W; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Bui JD; Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
  • Sears DD; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Olefsky JM; College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
  • Wang SE; Department of Family Medicine, University of California, San Diego, La Jolla, CA, USA.
Nat Cell Biol ; 24(6): 954-967, 2022 06.
Article in En | MEDLINE | ID: mdl-35637408
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / MicroRNAs / Diabetes Mellitus, Type 2 / Extracellular Vesicles Limits: Animals / Female / Humans Language: En Journal: Nat Cell Biol Year: 2022 Type: Article Affiliation country: United States
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / MicroRNAs / Diabetes Mellitus, Type 2 / Extracellular Vesicles Limits: Animals / Female / Humans Language: En Journal: Nat Cell Biol Year: 2022 Type: Article Affiliation country: United States