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Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway.
Chen, Bonan; Song, Yue; Zhan, Yujuan; Zhou, Shikun; Ke, Junzi; Ao, Weizhen; Zhang, Yigan; Liang, Qiqi; He, Minhui; Li, Shuhui; Xie, Fuda; Huang, Haonan; Chan, Wai Nok; Cheung, Alvin H K; Ma, Brigette B Y; Kang, Wei; To, Ka Fai; Xiao, Jianyong.
Affiliation
  • Chen B; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Department of Anatomical and Cellular Pathology, State Key Labo
  • Song Y; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • Zhan Y; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • Zhou S; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; School of Biomedical Sciences and Engineering, South China Univ
  • Ke J; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; iHuman Institute, School of Life Science and Technology, Shangh
  • Ao W; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; iHuman Institute, School of Life Science and Technology, Shangh
  • Zhang Y; The First School of Clinical Medicine, Lanzhou University, Lanzhou, 730000, PR China.
  • Liang Q; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • He M; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • Li S; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • Xie F; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • Huang H; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.
  • Chan WN; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
  • Cheung AHK; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
  • Ma BBY; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Department of Clinical Oncology, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
  • Kang W; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
  • To KF; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, PR China. Electronic address: kfto@cuhk.edu.hk.
  • Xiao J; Department of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Research Center of Integrative Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. Electronic address: jianyongxiao@gzucm.edu.cn.
Cancer Lett ; 543: 215783, 2022 09 01.
Article in En | MEDLINE | ID: mdl-35700820
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Limits: Animals / Humans Language: En Journal: Cancer Lett Year: 2022 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Limits: Animals / Humans Language: En Journal: Cancer Lett Year: 2022 Type: Article