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Allosteric modulation of GPCR-induced ß-arrestin trafficking and signaling by a synthetic intrabody.
Baidya, Mithu; Chaturvedi, Madhu; Dwivedi-Agnihotri, Hemlata; Ranjan, Ashutosh; Devost, Dominic; Namkung, Yoon; Stepniewski, Tomasz Maciej; Pandey, Shubhi; Baruah, Minakshi; Panigrahi, Bhanupriya; Sarma, Parishmita; Yadav, Manish K; Maharana, Jagannath; Banerjee, Ramanuj; Kawakami, Kouki; Inoue, Asuka; Selent, Jana; Laporte, Stéphane A; Hébert, Terence E; Shukla, Arun K.
Affiliation
  • Baidya M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Chaturvedi M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Dwivedi-Agnihotri H; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Ranjan A; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Devost D; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.
  • Namkung Y; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada.
  • Stepniewski TM; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.
  • Pandey S; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Warsaw, Poland.
  • Baruah M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Panigrahi B; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Sarma P; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Yadav MK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Maharana J; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Banerjee R; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Kawakami K; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.
  • Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
  • Selent J; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
  • Laporte SA; Research Program on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.
  • Hébert TE; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.
  • Shukla AK; Department of Medicine, McGill University Health Center, McGill University, Montréal, QC, H4A 3J1, Canada.
Nat Commun ; 13(1): 4634, 2022 08 08.
Article in En | MEDLINE | ID: mdl-35941121
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, G-Protein-Coupled Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Type: Article Affiliation country: India
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, G-Protein-Coupled Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Type: Article Affiliation country: India