Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs.

Bushin, Leah B; Covington, Brett C; Clark, Kenzie A; Caruso, Alessio; Seyedsayamdost, Mohammad R

Bushin, Leah B; Covington, Brett C; Clark, Kenzie A; Caruso, Alessio; Seyedsayamdost, Mohammad R.

Affiliation

Bushin LB; Department of Chemistry, Princeton University, Princeton, NJ, USA.
Covington BC; Department of Chemistry, Princeton University, Princeton, NJ, USA.
Clark KA; Department of Chemistry, Princeton University, Princeton, NJ, USA.
Caruso A; Department of Chemistry, Princeton University, Princeton, NJ, USA.
Seyedsayamdost MR; Department of Chemistry, Princeton University, Princeton, NJ, USA. mrseyed@princeton.edu.

Nat Chem Biol ; 18(10): 1135-1143, 2022 10.

Article in En | MEDLINE | ID: mdl-35953547

Subject(s)

Biological Products; Metalloproteins; Amides; Bacterial Proteins/metabolism; Biological Products/metabolism; Carbon; Cyclization; Ethers; Humans; Metalloproteins/metabolism; Nitrogen; Peptides/chemistry; S-Adenosylmethionine/metabolism; Streptococcus/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Metalloproteins Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2022 Type: Article Affiliation country: United States

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