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2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion.
Drazkowska, Karolina; Tomecki, Rafal; Warminski, Marcin; Baran, Natalia; Cysewski, Dominik; Depaix, Anaïs; Kasprzyk, Renata; Kowalska, Joanna; Jemielity, Jacek; Sikorski, Pawel J.
Affiliation
  • Drazkowska K; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
  • Tomecki R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Warminski M; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Baran N; Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw, Poland.
  • Cysewski D; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
  • Depaix A; Department of Environmental Microbiology and Biotechnology, Institute of Microbiology, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland.
  • Kasprzyk R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Kowalska J; Clinical Research Centre, Medical University of Bialystok, M. Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland.
  • Jemielity J; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
  • Sikorski PJ; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.
Nucleic Acids Res ; 50(16): 9051-9071, 2022 09 09.
Article in En | MEDLINE | ID: mdl-36018811
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Caps / Nucleotides Limits: Animals Language: En Journal: Nucleic Acids Res Year: 2022 Type: Article Affiliation country: Poland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Caps / Nucleotides Limits: Animals Language: En Journal: Nucleic Acids Res Year: 2022 Type: Article Affiliation country: Poland