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Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.
Needham, Edward J; Ren, Alexander L; Digby, Richard J; Norton, Emma J; Ebrahimi, Soraya; Outtrim, Joanne G; Chatfield, Doris A; Manktelow, Anne E; Leibowitz, Maya M; Newcombe, Virginia F J; Doffinger, Rainer; Barcenas-Morales, Gabriela; Fonseca, Claudia; Taussig, Michael J; Burnstein, Rowan M; Samanta, Romit J; Dunai, Cordelia; Sithole, Nyarie; Ashton, Nicholas J; Zetterberg, Henrik; Gisslén, Magnus; Edén, Arden; Marklund, Emelie; Openshaw, Peter J M; Dunning, Jake; Griffiths, Michael J; Cavanagh, Jonathan; Breen, Gerome; Irani, Sarosh R; Elmer, Anne; Kingston, Nathalie; Summers, Charlotte; Bradley, John R; Taams, Leonie S; Michael, Benedict D; Bullmore, Edward T; Smith, Kenneth G C; Lyons, Paul A; Coles, Alasdair J; Menon, David K.
Affiliation
  • Needham EJ; Department of Clinical Neurosciences, University of Cambridge, UK.
  • Ren AL; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Digby RJ; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Norton EJ; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Ebrahimi S; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Outtrim JG; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Chatfield DA; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Manktelow AE; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Leibowitz MM; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Newcombe VFJ; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Doffinger R; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Barcenas-Morales G; Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.
  • Fonseca C; Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.
  • Taussig MJ; Cambridge Protein Arrays Ltd, Babraham Research Campus, Cambridge, UK.
  • Burnstein RM; Cambridge Protein Arrays Ltd, Babraham Research Campus, Cambridge, UK.
  • Samanta RJ; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Dunai C; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK.
  • Sithole N; Clinical Infection Microbiology and Neuroimmunology, Institute of Infection, Veterinary and Ecological Science, Liverpool, UK.
  • Ashton NJ; Department of Infectious Diseases, Cambridge University NHS Hospitals Foundation Trust, Cambridge, UK.
  • Zetterberg H; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
  • Gisslén M; Jeffrey Cheah Biomedical Centre, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, UK.
  • Edén A; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
  • Marklund E; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
  • Openshaw PJM; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
  • Dunning J; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.
  • Griffiths MJ; UK Dementia Research Institute at UCL, London, UK.
  • Cavanagh J; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.
  • Breen G; Department of Infectious Diseases, Institute of Biomedicine, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
  • Irani SR; Department of Infectious Diseases, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Elmer A; Department of Infectious Diseases, Institute of Biomedicine, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
  • Kingston N; Department of Infectious Diseases, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Summers C; Department of Infectious Diseases, Institute of Biomedicine, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
  • Bradley JR; Department of Infectious Diseases, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Taams LS; National Heart and Lung Institute, Imperial College London, London, UK.
  • Michael BD; Nuffield Department of Medicine, Pandemic Sciences Institute, University of Oxford, Oxford, UK.
  • Bullmore ET; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Smith KGC; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Lyons PA; Department of Social Genetic and Developmental Psychiatry, King's College London, London, UK.
  • Coles AJ; Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  • Menon DK; Department of Neurology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Brain ; 145(11): 4097-4107, 2022 11 21.
Article in En | MEDLINE | ID: mdl-36065116
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Influenza, Human / COVID-19 Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Brain Year: 2022 Type: Article Affiliation country: United kingdom
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Influenza, Human / COVID-19 Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Brain Year: 2022 Type: Article Affiliation country: United kingdom