[Honokiol reduces doxorubicin-induced cardiotoxicity <i>in vitro</i> by inhibiting pyroptosis <i>via</i> activating AMPK/Nrf2 signaling].

Xiong, F; Liu, R; Li, Y; Sun, N

[Honokiol reduces doxorubicin-induced cardiotoxicity in vitro by inhibiting pyroptosis via activating AMPK/Nrf2 signaling].

Xiong, F; Liu, R; Li, Y; Sun, N.

Affiliation

Xiong F; Department of Pharmacy, Xi'an Children's Hospital, Xi'an 710003, China.
Liu R; Department of Nutrition, Xi'an Children's Hospital, Xi'an 710003, China.
Li Y; Department of Pharmacy, Xi'an Children's Hospital, Xi'an 710003, China.
Sun N; Institute of Basic Medical Science, Xi'an Medical University, Xi'an 710021, China.

Nan Fang Yi Ke Da Xue Xue Bao ; 42(8): 1205-1211, 2022 Aug 20.

Article in Zh | MEDLINE | ID: mdl-36073220

Subject(s)

Cardiotoxicity; Pyroptosis; AMP-Activated Protein Kinases/metabolism; Allyl Compounds; Biphenyl Compounds; Cardiotoxicity/metabolism; Cardiotoxicity/pathology; Caspase 3/metabolism; Cytochromes c; Doxorubicin/adverse effects; Humans; Interleukin-6/metabolism; Myocytes, Cardiac; NF-E2-Related Factor 2/metabolism; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism; Phenols; RNA, Messenger/metabolism; Tumor Necrosis Factor-alpha/metabolism

Key words

cardiotoxicity; doxorubicin; honokiol; pyroptosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiotoxicity / Pyroptosis Limits: Humans Language: Zh Journal: Nan Fang Yi Ke Da Xue Xue Bao Year: 2022 Type: Article Affiliation country: China

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