Sulodexide Increases Glutathione Synthesis and Causes Pro-Reducing Shift in Glutathione-Redox State in HUVECs Exposed to Oxygen-Glucose Deprivation: Implication for Protection of Endothelium against Ischemic Injury.

Bontor, Klaudia; Gabryel, Bozena

Bontor, Klaudia; Gabryel, Bozena.

Affiliation

Bontor K; Department of Pharmacology, School of Medicine in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.
Gabryel B; Department of Pharmacology, School of Medicine in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.

Molecules ; 27(17)2022 Aug 25.

Article in En | MEDLINE | ID: mdl-36080234

Subject(s)

Endothelial Cells; Glucose; Endothelium/metabolism; Glucose/metabolism; Glutathione/metabolism; Glutathione Disulfide/metabolism; Glycosaminoglycans/metabolism; Glycosaminoglycans/pharmacology; Humans; Ischemia/metabolism; Oxidation-Reduction; Oxidative Stress; Oxygen/metabolism

Key words

GCLc; GSH; GSS; GSSG; apoptosis; endothelial cells; ischemia; oxidative stress; redox potential; sulodexide

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelial Cells / Glucose Type of study: Etiology_studies Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: Poland

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