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A RUNX1-FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies.
Lee, Byung-Chul; Zhou, Yifan; Bresciani, Erica; Ozkaya, Neval; Dulau-Florea, Alina; Carrington, Blake; Shin, Tae-Hoon; Baena, Valentina; Syed, Zulfeqhar A; Hong, So Gun; Zhen, Tao; Calvo, Katherine R; Liu, Paul; Dunbar, Cynthia E.
Affiliation
  • Lee BC; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
  • Zhou Y; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
  • Bresciani E; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, United Kingdom.
  • Ozkaya N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
  • Dulau-Florea A; Oncogenesis and Development Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
  • Carrington B; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Shin TH; Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD.
  • Baena V; Zebrafish Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
  • Syed ZA; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
  • Hong SG; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Jeju National University, Jeju, Republic of Korea.
  • Zhen T; Electron Microscopy Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
  • Calvo KR; Electron Microscopy Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
  • Liu P; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
  • Dunbar CE; Oncogenesis and Development Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
Blood ; 141(3): 231-237, 2023 01 19.
Article in En | MEDLINE | ID: mdl-36322931
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Core Binding Factor Alpha 2 Subunit Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2023 Type: Article Affiliation country: Moldova
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Core Binding Factor Alpha 2 Subunit Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2023 Type: Article Affiliation country: Moldova