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RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.
Kim, Yoon A; Siddiqui, Tohid; Blaze, Jennifer; Cosacak, Mehmet Ilyas; Winters, Tristan; Kumar, Atul; Tein, Ellen; Sproul, Andrew A; Teich, Andrew F; Bartolini, Francesca; Akbarian, Schahram; Kizil, Caghan; Hargus, Gunnar; Santa-Maria, Ismael.
Affiliation
  • Kim YA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.
  • Siddiqui T; Department of Pathology and Cell Biology, Columbia University, New York, USA.
  • Blaze J; German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Dresden, Germany.
  • Cosacak MI; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Winters T; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Kumar A; German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Dresden, Germany.
  • Tein E; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.
  • Sproul AA; Department of Pathology and Cell Biology, Columbia University, New York, USA.
  • Teich AF; Department of Pathology and Cell Biology, Columbia University, New York, USA.
  • Bartolini F; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.
  • Akbarian S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.
  • Kizil C; Department of Pathology and Cell Biology, Columbia University, New York, USA.
  • Hargus G; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.
  • Santa-Maria I; Department of Pathology and Cell Biology, Columbia University, New York, USA.
Acta Neuropathol ; 145(1): 29-48, 2023 01.
Article in En | MEDLINE | ID: mdl-36357715
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MicroRNAs / Induced Pluripotent Stem Cells / Alzheimer Disease Limits: Adult / Animals / Humans Language: En Journal: Acta Neuropathol Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MicroRNAs / Induced Pluripotent Stem Cells / Alzheimer Disease Limits: Adult / Animals / Humans Language: En Journal: Acta Neuropathol Year: 2023 Type: Article Affiliation country: United States