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Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress.
Pitts, Stephanie; Liu, Hester; Ibrahim, Adel; Garg, Amit; Felgueira, Catarina Mendes; Begum, Asma; Fan, Wenjun; Teh, Selina; Low, Jin-Yih; Ford, Brittany; Schneider, David A; Hay, Ronald; Laiho, Marikki.
Affiliation
  • Pitts S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Liu H; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Ibrahim A; Centre for Gene Regulation and Expression, University of Dundee, Dundee, Scotland, United Kingdom.
  • Garg A; Centre for Gene Regulation and Expression, University of Dundee, Dundee, Scotland, United Kingdom.
  • Felgueira CM; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Begum A; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Fan W; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Teh S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Low JY; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Ford B; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
  • Schneider DA; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Hay R; Centre for Gene Regulation and Expression, University of Dundee, Dundee, Scotland, United Kingdom.
  • Laiho M; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland. Electronic address: mlaiho1@jhmi.edu.
J Biol Chem ; 298(12): 102690, 2022 12.
Article in En | MEDLINE | ID: mdl-36372232
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / SKP Cullin F-Box Protein Ligases / F-Box Proteins Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / SKP Cullin F-Box Protein Ligases / F-Box Proteins Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Type: Article Affiliation country: United States