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In Vitro Model Systems to Study Human T Cell Development.
Lambrechts, Nina; Liang, Kai Ling; Velghe, Imke; Strubbe, Steven; Dolens, Anne-Catherine; Taghon, Tom.
Affiliation
  • Lambrechts N; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium.
  • Liang KL; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium.
  • Velghe I; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium.
  • Strubbe S; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium.
  • Dolens AC; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium.
  • Taghon T; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium. Tom.Taghon@ugent.be.
Methods Mol Biol ; 2580: 335-354, 2023.
Article in En | MEDLINE | ID: mdl-36374468
ABSTRACT
Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of the specific aspects that need attention when performing T cell differentiation cultures with human hematopoietic and T cell progenitors.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Intercellular Signaling Peptides and Proteins Limits: Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Intercellular Signaling Peptides and Proteins Limits: Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article Affiliation country: Belgium