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Differences in rectoanal inhibitory reflex duration between patients with refractory functional constipationand myelomeningocele. / Diferencias en la duración del reflejo rectoanal inhibitorio en pacientes con constipación funcional refractaria y mielomeningocele.
Fernández, Julián; Messere, Gabriela; Ortiz, Gonzalo; Oviedo, Adriana; Vidal, Jorge; Morise, Silvia; Nurko, Samuel; Bigliardi, Román.
Affiliation
  • Fernández J; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
  • Messere G; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
  • Ortiz G; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
  • Oviedo A; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
  • Vidal J; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
  • Morise S; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
  • Nurko S; Center for Motility and Functional Gastrointestinal Disorders, Boston Children´s Hospital, Harvard Medical School, Boston, United States.
  • Bigliardi R; Department of Pediatric Gastroenterology. Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
Arch Argent Pediatr ; 121(2): e202202598, 2023 04 01.
Article in En, Es | MEDLINE | ID: mdl-36413143
ABSTRACT
Introduction. Usually, during anorectal manometry, only the presence or absence of rectoanal inhibitory reflex (RAIR) is investigated. Studies have reported that a detailed analysis may provide data of interest. Our hypothesis is that RAIR measurement may provide information to detect organic causes (tethered cord, lipoma, etc.) in patients in whom a functional cause had been previously considered. Objectives. To compare RAIR duration in anorectal manometry between patients with refractory functional constipation (RFC) and myelomeningocele (MMC). Population and methods. Observational, analytical, cross-sectional study (2004-2019). Patients with chronic constipation and functional and organic fecal incontinence (myelomeningocele). The anorectal manometry was performed with a water-perfused system, and the duration of RAIR was measured with different volumes (20, 40, and 60 cc). Group 1 (G1) 81 RFC. Group 2 (G2) 54 MMC. Patients with developmental delay, compliant anal sphincter, sacral agenesis and non-cooperative patients were excluded. Results. A total of 135 individuals were included (62 were male). Their median age was 9.57 years in G1 and 9.63 years in G2. Average duration in G1 versus G2 with 20 cc 8.89 versus 15.21 seconds; 40 cc 11.41 versus 21.12 seconds; 60 cc 14.15 versus 26.02 seconds. The difference in RAIR duration with the varying volumes was statistically significant (p = 0.0001). Conclusion. RAIR duration was longer with increasing balloon inflation volumes in both populations. RAIR duration was longer in patients with MMC than in those with RFC. Spinal injury should be ruled out in patients with prolonged RAIR.
RESUMEN
Introducción. Habitualmente, durante la manometría anorrectal, en lo correspondiente al reflejo rectoanal inhibitorio (RRAI) solo se pesquisa su presencia o ausencia. Estudios han reportado que su análisis detallado puede brindar datos de interés. Nuestra hipótesis es que la medición del RRAI puede dar información para reconocer causas orgánicas (médula anclada, lipoma, etc.) en pacientes en los que previamente se consideró como de causa funcional. Objetivos. Comparar la duración del reflejo rectoanal inhibitorio en la manometría anorrectal de pacientes con constipación funcional refractaria (CFR) y mielomeningocele (MMC). Población y métodos. Estudio observacional, transversal, analítico (2004-2019). Pacientes constipados crónicos con incontinencia fecal funcional y orgánica (mielomeningocele). Se les realizó manometría anorrectal con sistema de perfusión de agua y se midió la duración del RRAI con diferentes volúmenes (20, 40 y 60 cc). Grupo 1 (G1) 81 CFR. Grupo 2 (G2) 54 MMC. Se excluyeron pacientes con retraso madurativo, esfínter anal complaciente, agenesia sacra y aquellos no colaboradores. Resultados. Se incluyeron 135 sujetos (62 varones). La mediana de edad fue G19,57 años; G2 9,63 años. Duración promedio G1 vs. G2 con 20 cc 8,89 vs. 15,21 segundos; con 40 cc 11.41 vs. 21,12 segundos; con 60 cc 14,15 vs. 26,02 segundos. La diferencia de duración del RRAI entre ambos grupos con diferentes volúmenes fue estadísticamente significativa (p = 0,0001). Conclusión. La duración del RRAI aumenta a mayor volumen de insuflación del balón en ambas poblaciones. Pacientes con MMC tuvieron mayor duración del RRAI que aquellos con CFR. En los pacientes con RRAI prolongado, debe descartarse lesión medular.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anal Canal / Rectum / Meningomyelocele / Constipation Type of study: Observational_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En / Es Journal: Arch Argent Pediatr Year: 2023 Type: Article Affiliation country: Argentina

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anal Canal / Rectum / Meningomyelocele / Constipation Type of study: Observational_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En / Es Journal: Arch Argent Pediatr Year: 2023 Type: Article Affiliation country: Argentina