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Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels.
Yao, Xia; Gao, Shuai; Wang, Jixin; Li, Zhangqiang; Huang, Jian; Wang, Yan; Wang, Zhifei; Chen, Jiaofeng; Fan, Xiao; Wang, Weipeng; Jin, Xueqin; Pan, Xiaojing; Yu, Yong; Lagrutta, Armando; Yan, Nieng.
Affiliation
  • Yao X; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
  • Gao S; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address: gaoshuai812@whu.edu.cn.
  • Wang J; Department of Genetic and Cellular Toxicology, ADME & Discovery Toxicology, Preclinical Development, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Li Z; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Huang J; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
  • Wang Y; Department of Biological Sciences, St. John's University, Queens, NY 11439, USA.
  • Wang Z; Department of Biological Sciences, St. John's University, Queens, NY 11439, USA.
  • Chen J; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Fan X; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
  • Wang W; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Jin X; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Pan X; State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Yu Y; Department of Biological Sciences, St. John's University, Queens, NY 11439, USA.
  • Lagrutta A; Department of Genetic and Cellular Toxicology, ADME & Discovery Toxicology, Preclinical Development, Merck Research Laboratories, Merck & Co., Inc., West Point, PA 19486, USA.
  • Yan N; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address: nyan@princeton.edu.
Cell ; 185(25): 4801-4810.e13, 2022 Dec 08.
Article in En | MEDLINE | ID: mdl-36417914
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sofosbuvir / Amiodarone Language: En Journal: Cell Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sofosbuvir / Amiodarone Language: En Journal: Cell Year: 2022 Type: Article Affiliation country: United States