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The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation.
Goh, Joleen P Z; Ruchti, Fiorella; Poh, Si En; Koh, Winston L C; Tan, Kiat Yi; Lim, Yan Ting; Thng, Steven T G; Sobota, Radoslaw M; Hoon, Shawn S; Liu, Chenxi; O'Donoghue, Anthony J; LeibundGut-Landmann, Salomé; Oon, Hazel H; Li, Hao; Dawson, Thomas L.
Affiliation
  • Goh JPZ; A*STAR Skin Research Labs, Agency for Science, Technology and Research, Singapore 138648.
  • Ruchti F; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore 308232.
  • Poh SE; Section of Immunology, Vetsuisse Faculty and Institute of Experimental Immunology, University of Zürich, Zürich CH-8057, Switzerland.
  • Koh WLC; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673.
  • Tan KY; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research, Singapore 138669.
  • Lim YT; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore 138671.
  • Thng STG; Functional Proteomics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673.
  • Sobota RM; Functional Proteomics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673.
  • Hoon SS; National Skin Centre, National Healthcare Group, Singapore 308205.
  • Liu C; Skin Research Institute of Singapore, Agency for Science, Technology and Research, Singapore 308232.
  • O'Donoghue AJ; Functional Proteomics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673.
  • LeibundGut-Landmann S; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673.
  • Oon HH; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093-0657.
  • Li H; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093-0657.
  • Dawson TL; Section of Immunology, Vetsuisse Faculty and Institute of Experimental Immunology, University of Zürich, Zürich CH-8057, Switzerland.
Proc Natl Acad Sci U S A ; 119(49): e2212533119, 2022 12 06.
Article in En | MEDLINE | ID: mdl-36442106

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dermatitis, Atopic / Aspartic Acid Proteases / Malassezia Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dermatitis, Atopic / Aspartic Acid Proteases / Malassezia Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article