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Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition.
Tocci, Piera; Roman, Celia; Sestito, Rosanna; Di Castro, Valeriana; Sacconi, Andrea; Molineris, Ivan; Paolini, Francesca; Carosi, Mariantonia; Tonon, Giovanni; Blandino, Giovanni; Bagnato, Anna.
Affiliation
  • Tocci P; Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, Rome, Italy. piera.tocci@ifo.it.
  • Roman C; Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, Rome, Italy.
  • Sestito R; Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, Rome, Italy.
  • Di Castro V; Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, Rome, Italy.
  • Sacconi A; Translational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
  • Molineris I; Department of Life Science and System Biology, University of Turin, Turin, Italy.
  • Paolini F; Tumor Immunology and Immunotherapy Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
  • Carosi M; Pathology Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
  • Tonon G; Center for Omics Sciences (COSR) and Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Blandino G; Università Vita-Salute San Raffaele, 20132, Milan, Italy.
  • Bagnato A; Translational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Cell Death Dis ; 14(1): 5, 2023 01 05.
Article in En | MEDLINE | ID: mdl-36604418
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Poly(ADP-ribose) Polymerase Inhibitors Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Cell Death Dis Year: 2023 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Poly(ADP-ribose) Polymerase Inhibitors Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Cell Death Dis Year: 2023 Type: Article Affiliation country: Italy