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DNA methylation analysis is used to identify novel genetic loci associated with circulating fibrinogen levels in blood.
Hahn, Julie; Bressler, Jan; Domingo-Relloso, Arce; Chen, Ming-Huei; McCartney, Daniel L; Teumer, Alexander; van Dongen, Jenny; Kleber, Marcus E; Aïssi, Dylan; Swenson, Brenton R; Yao, Jie; Zhao, Wei; Huang, Jian; Xia, Yujing; Brown, Michael R; Costeira, Ricardo; de Geus, Eco J C; Delgado, Graciela E; Dobson, Dre'Von A; Elliott, Paul; Grabe, Hans J; Guo, Xiuqing; Harris, Sarah E; Huffman, Jennifer E; Kardia, Sharon L R; Liu, Yongmei; Lorkowski, Stefan; Marioni, Riccardo E; Nauck, Matthias; Ratliff, Scott M; Sabater-Lleal, Maria; Spector, Tim D; Suchon, Pierre; Taylor, Kent D; Thibord, Florian; Trégouët, David-Alexandre; Wiggins, Kerri L; Willemsen, Gonneke; Bell, Jordana T; Boomsma, Dorret I; Cole, Shelley A; Cox, Simon R; Dehghan, Abbas; Greinacher, Andreas; Haack, Karin; März, Winfried; Morange, Pierre-Emmanuel; Rotter, Jerome I; Sotoodehnia, Nona; Tellez-Plaza, Maria.
Affiliation
  • Hahn J; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA. Electronic address: Julie.M.Hahn@uth.tmc.edu.
  • Bressler J; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Domingo-Relloso A; Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA; Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes, Madrid, Spain; Department of Statistics and Operations Research, Uni
  • Chen MH; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA.
  • McCartney DL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom.
  • Teumer A; Department SHIP/Clinical-Epidemiological Research, Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany; Department of Population Medicine and Lifestyle Diseases Preventio
  • van Dongen J; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
  • Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany.
  • Aïssi D; Univ. Bordeaux, INSERM, Bordeaux Population Health Research Center, UMR 1219, Molecular Epidemiology of Vascular and Brain Disorders, Bordeaux, France.
  • Swenson BR; Cardiovascular Health Research Unit, School of Public Health, University of Washington, Seattle, Washington, USA.
  • Yao J; Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
  • Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
  • Huang J; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
  • Xia Y; Department of Twin Research and Genetic Epidemiology, St Thomas Hospital Campus, King's College London, London, United Kingdom.
  • Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Costeira R; Department of Twin Research and Genetic Epidemiology, St Thomas Hospital Campus, King's College London, London, United Kingdom.
  • de Geus EJC; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
  • Delgado GE; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Dobson DA; Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Elliott P; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom; UK Dementia Research Institute, Imperial College London, London, United Kingdom; British Heart Foundation Centre for Research Excellence, Imp
  • Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.
  • Guo X; Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
  • Harris SE; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.
  • Huffman JE; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA.
  • Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
  • Liu Y; Medicine, Cardiology, Duke Molecular Physiology Institute, Durham, North Carolina, USA.
  • Lorkowski S; Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
  • Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom.
  • Nauck M; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Ratliff SM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
  • Sabater-Lleal M; Genomics of Complex Disease Unit, Sant Pau Biomedical Research Institute (IIB Sant Pau), Barcelona, Spain; Department of Medicine, Cardiovascular Medicine Unit, Karolinska Institutet, Stockholm, Sweden.
  • Spector TD; Department of Twin Research and Genetic Epidemiology, St Thomas Hospital Campus, King's College London, London, United Kingdom.
  • Suchon P; Center for CardioVascular and Nutrition research (C2VN), INSERM 1263, INRAE 1260, Hematology Laboratory, La Timone University Hospital of Marseille, Aix-Marseille University, Marseille, France.
  • Taylor KD; Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
  • Thibord F; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, Massachusetts, USA.
  • Trégouët DA; Univ. Bordeaux, INSERM, Bordeaux Population Health Research Center, UMR 1219, Molecular Epidemiology of Vascular and Brain Disorders, Bordeaux, France.
  • Wiggins KL; Department of Medicine, Division of General Internal Medicine, University of Washington, Seattle, Washington, USA.
  • Willemsen G; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
  • Bell JT; Department of Twin Research and Genetic Epidemiology, St Thomas Hospital Campus, King's College London, London, United Kingdom.
  • Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
  • Cole SA; Population Health Program, Texas Biomedical Research Institute, San Antonio, Texas, USA.
  • Cox SR; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.
  • Dehghan A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
  • Greinacher A; Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Haack K; Population Health Program, Texas Biomedical Research Institute, San Antonio, Texas, USA.
  • März W; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; SYNLAB Academy, SYNLAB Holding Deutschland GmbH, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
  • Morange PE; Cardiovascular and Nutrition Reserach Center (C2VN), INSERM, INRAE, Aix-Marseille University, Marseille, France.
  • Rotter JI; Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
  • Sotoodehnia N; Department of Medicine, Division of Cardiology, University of Washington, Seattle, Washington, USA.
  • Tellez-Plaza M; Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes, Madrid, Spain.
J Thromb Haemost ; 21(5): 1135-1147, 2023 05.
Article in En | MEDLINE | ID: mdl-36716967
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Epigenesis, Genetic Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2023 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Epigenesis, Genetic Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2023 Type: Article