CNKSR2, a downstream mediator of retinoic acid signaling, modulates the Ras/Raf/MEK pathway to regulate patterning and invagination of the chick forebrain roof plate.

Udaykumar, Niveda; Zaidi, Mohd Ali Abbas; Rai, Aishwarya; Sen, Jonaki

Udaykumar, Niveda; Zaidi, Mohd Ali Abbas; Rai, Aishwarya; Sen, Jonaki.

Affiliation

Udaykumar N; Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016 Uttar Pradesh, India.
Zaidi MAA; Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016 Uttar Pradesh, India.
Rai A; Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016 Uttar Pradesh, India.
Sen J; Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016 Uttar Pradesh, India.

Development ; 150(3)2023 02 15.

Article in En | MEDLINE | ID: mdl-36734326

Subject(s)

Adaptor Proteins, Signal Transducing; Holoprosencephaly; Prosencephalon; Tretinoin; Animals; Chick Embryo; Adaptor Proteins, Signal Transducing/metabolism; Holoprosencephaly/genetics; Mitogen-Activated Protein Kinase Kinases/genetics; Mitogen-Activated Protein Kinase Kinases/metabolism; Prosencephalon/embryology; Tretinoin/metabolism

Key words

CNKSR2; Chick embryo; Forebrain; Patterning; Ras/Raf/MEK signaling; Retinoic acid signaling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tretinoin / Holoprosencephaly / Prosencephalon / Adaptor Proteins, Signal Transducing Limits: Animals Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2023 Type: Article Affiliation country: India

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