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Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug-induced heart rate changes.
Brooks, Logan; Dolton, Michael; Langenhorst, Jurgen; Yoshida, Kenta; Lien, Yi Ting Kayla; Malhi, Vikram; Li, Chunze; Perez-Moreno, Pablo; Bond, John; Chen, Ya-Chi; Yu, Jiajie.
Affiliation
  • Brooks L; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Dolton M; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Langenhorst J; Pharmetheus AB, Uppsala, Sweden.
  • Yoshida K; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Lien YTK; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Malhi V; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Li C; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Perez-Moreno P; Product Development Oncology, Genentech, Inc., South San Francisco, California, USA.
  • Bond J; Product Development Oncology, Genentech, Inc., South San Francisco, California, USA.
  • Chen YC; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Yu J; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
Clin Transl Sci ; 16(5): 823-834, 2023 05.
Article in En | MEDLINE | ID: mdl-36772881
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Long QT Syndrome / Fluoroquinolones Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Clin Transl Sci Year: 2023 Type: Article Affiliation country: United States
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Long QT Syndrome / Fluoroquinolones Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Clin Transl Sci Year: 2023 Type: Article Affiliation country: United States