New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany.

Heinrich, Fabian; Huter, Tobias; Mertens, Sophie; Lange, Philine; Vering, Jessica; Heinemann, Axel; Nörz, Dominik Sebastian; Hoffmann, Armin; Aepfelbacher, Martin; Ondruschka, Benjamin; Krasemann, Susanne; Lütgehetmann, Marc

Heinrich, Fabian; Huter, Tobias; Mertens, Sophie; Lange, Philine; Vering, Jessica; Heinemann, Axel; Nörz, Dominik Sebastian; Hoffmann, Armin; Aepfelbacher, Martin; Ondruschka, Benjamin; Krasemann, Susanne; Lütgehetmann, Marc.

Emerg Infect Dis ; 29(3): 652-656, 2023 03.

Article in En | MEDLINE | ID: mdl-36787498

ABSTRACT

ABSTRACT

We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.

Subject(s)

COVID-19; SARS-CoV-2; Humans; Autopsy; COVID-19 Vaccines; Germany

Key words

Alpha variant; B.1.1.529; B.1.1.7; B.1.617.2; COVID-19; Delta variant; Germany; Omicron variant; SARS; SARS-CoV-2; VOC; coronavirus; coronavirus disease; organ tropism; pulmonary damage; respiratory infections; severe acute respiratory syndrome coronavirus 2; variants of concern; viral load; viruses; zoonoses

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Country/Region as subject: Europa Language: En Journal: Emerg Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Type: Article

Fulltext

XML

PubMed Links

Search on Google