Heterocyclic Hemipiperazines: Water-Compatible Peptide-Derived Photoswitches.
Chemistry
; 29(26): e202204009, 2023 May 08.
Article
in En
| MEDLINE
| ID: mdl-36790823
ABSTRACT
Hemipiperazines are a recently discovered class of peptide-derived molecular photoswitches with high biocompatibility and therapeutic potential. Here, for the first time we describe photochromism of heterocyclic hemipiperazines. They demonstrate long thermal lifetimes, and enlarged band separation between photoisomers. Efficient photoisomerization occurs under aqueous conditions, although with a need for organic co-solvent. Bidirectional switching with visible light is observed for an extended aromatic system.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Water
/
Light
Language:
En
Journal:
Chemistry
Journal subject:
QUIMICA
Year:
2023
Type:
Article
Affiliation country:
Germany