How I treat refractory/relapsed diffuse large B-cell lymphomas with CD19-directed chimeric antigen receptor T cells.

Nagler, Arnon; Perriello, Vincenzo Maria; Falini, Lorenza; Falini, Brunangelo

Nagler, Arnon; Perriello, Vincenzo Maria; Falini, Lorenza; Falini, Brunangelo.

Affiliation

Nagler A; Division of Hematology, Sheba Medical Center, Tel Hashomer, Israel.
Perriello VM; Institute of Hematology and Center for Hemato-Oncology Research, University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy.
Falini L; Institute of Hematology and Center for Hemato-Oncology Research, University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy.
Falini B; Institute of Hematology and Center for Hemato-Oncology Research, University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy.

Br J Haematol ; 201(3): 396-410, 2023 05.

Article in En | MEDLINE | ID: mdl-36916189

Subject(s)

Lymphoma, Large B-Cell, Diffuse; Receptors, Chimeric Antigen; Humans; Receptors, Chimeric Antigen/therapeutic use; Receptors, Antigen, T-Cell/therapeutic use; Neoplasm Recurrence, Local/etiology; Lymphoma, Large B-Cell, Diffuse/drug therapy; T-Lymphocytes; Immunotherapy, Adoptive/methods; Antigens, CD19

Key words

CD19; Chimeric antigen receptor (CAR) T cells; cytokine release syndrome (CRS); immune effector cell-associated neurotoxicity syndrome (ICANS); immunohistochemistry; lymphoma; monoclonal antibodies

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Receptors, Chimeric Antigen Type of study: Etiology_studies / Prognostic_studies Limits: Humans Language: En Journal: Br J Haematol Year: 2023 Type: Article Affiliation country: Israel

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