Zonisamide-induced distal renal tubular acidosis and critical hypokalaemia.
BMJ Case Rep
; 16(4)2023 Apr 11.
Article
in En
| MEDLINE
| ID: mdl-37041041
ABSTRACT
A woman in her 20s presented with rapidly progressive muscle weakness and a 1-month preceding history of fatigability, nausea and vomiting. She was found to have critical hypokalaemia (K+ 1.8 mmol/L), a prolonged corrected QT interval (581 ms) and a normal anion gap metabolic acidosis (pH 7.15) due to zonisamide-induced distal (type 1) renal tubular acidosis. She was admitted to the intensive care unit for potassium replacement and alkali therapy. Clinical and biochemical improvement ensued, and she was discharged after a 27-day inpatient stay.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Acidosis
/
Acidosis, Renal Tubular
/
Hypokalemia
Limits:
Female
/
Humans
Language:
En
Journal:
BMJ Case Rep
Year:
2023
Type:
Article
Affiliation country:
Ireland