Adrenergic regulation of astroglial aerobic glycolysis and lipid metabolism: Towards a noradrenergic hypothesis of neurodegeneration.

Zorec, Robert; Vardjan, Nina

Zorec, Robert; Vardjan, Nina.

Affiliation

Zorec R; Laboratory of Neuroendocrinology - Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; Laboratory of Cell Engineering, Celica Biomedical, Ljubljana, Slovenia. Electronic address: robert.zorec@mf.uni-lj.si.
Vardjan N; Laboratory of Neuroendocrinology - Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; Laboratory of Cell Engineering, Celica Biomedical, Ljubljana, Slovenia. Electronic address: nina.vardjan@mf.uni-lj.si.

Neurobiol Dis ; 182: 106132, 2023 06 15.

Article in En | MEDLINE | ID: mdl-37094775

Subject(s)

Adrenergic Agents; Alzheimer Disease; Humans; Astrocytes/metabolism; Lipid Metabolism; Norepinephrine/metabolism; Alzheimer Disease/metabolism; Locus Coeruleus/metabolism; Glycolysis/physiology

Key words

Alzheimer's disease; Cognitive decline; L-Lactate production; Lipid droplet; Neurodegeneration; Warburg effect

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adrenergic Agents / Alzheimer Disease Limits: Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2023 Type: Article

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