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A human iPSC-derived hepatocyte screen identifies compounds that inhibit production of Apolipoprotein B.
Liu, Jui-Tung; Doueiry, Caren; Jiang, Yu-Lin; Blaszkiewicz, Josef; Lamprecht, Mary Paige; Heslop, James A; Peterson, Yuri K; Carten, Juliana Debrito; Traktman, Paula; Yuan, Yang; Khetani, Salman R; Twal, Waleed O; Duncan, Stephen A.
Affiliation
  • Liu JT; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Doueiry C; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Jiang YL; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Blaszkiewicz J; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Lamprecht MP; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Heslop JA; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Peterson YK; Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Carten JD; Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Traktman P; Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.
  • Yuan Y; Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Khetani SR; Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, 60607, USA.
  • Twal WO; Grùthan Biosciences LLC, Hollywood, SC, 29449, USA.
  • Duncan SA; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29425, USA. duncanst@musc.edu.
Commun Biol ; 6(1): 452, 2023 04 24.
Article in En | MEDLINE | ID: mdl-37095219
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells / Homozygous Familial Hypercholesterolemia / Hyperlipoproteinemia Type II / Anticholesteremic Agents Limits: Animals / Humans Language: En Journal: Commun Biol Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells / Homozygous Familial Hypercholesterolemia / Hyperlipoproteinemia Type II / Anticholesteremic Agents Limits: Animals / Humans Language: En Journal: Commun Biol Year: 2023 Type: Article Affiliation country: United States