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Applying Lipidomics to Non-Alcoholic Fatty Liver Disease: A Clinical Perspective.
Huang, Jian; Sigon, Giordano; Mullish, Benjamin H; Wang, Dan; Sharma, Rohini; Manousou, Pinelopi; Forlano, Roberta.
Affiliation
  • Huang J; Liver Unit, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W21NY, UK.
  • Sigon G; Liver Unit, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W21NY, UK.
  • Mullish BH; Liver Unit, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W21NY, UK.
  • Wang D; Liver Unit, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W21NY, UK.
  • Sharma R; Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London W21NY, UK.
  • Manousou P; Liver Unit, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W21NY, UK.
  • Forlano R; Liver Unit, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W21NY, UK.
Nutrients ; 15(8)2023 Apr 20.
Article in En | MEDLINE | ID: mdl-37111211
ABSTRACT
The prevalence of Non-alcoholic fatty liver disease (NAFLD) and associated complications, such as hepatocellular carcinoma (HCC), is growing worldwide, due to the epidemics of metabolic risk factors, such as obesity and type II diabetes. Among other factors, an aberrant lipid metabolism represents a crucial step in the pathogenesis of NAFLD and the development of HCC in this population. In this review, we summarize the evidence supporting the application of translational lipidomics in NAFLD patients and NAFLD associated HCC in clinical practice.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Diabetes Mellitus, Type 2 / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Nutrients Year: 2023 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Diabetes Mellitus, Type 2 / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Nutrients Year: 2023 Type: Article Affiliation country: United kingdom