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In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40.
Wu, Jennifer E; Manne, Sasikanth; Ngiow, Shin Foong; Baxter, Amy E; Huang, Hua; Freilich, Elizabeth; Clark, Megan L; Lee, Joanna H; Chen, Zeyu; Khan, Omar; Staupe, Ryan P; Huang, Yinghui J; Shi, Junwei; Giles, Josephine R; Wherry, E John.
Affiliation
  • Wu JE; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Manne S; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Ngiow SF; Parker Institute for Cancer Immunotherapy at University of Pennsylvania; Philadelphia, PA, USA.
  • Baxter AE; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Huang H; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Freilich E; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Clark ML; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Lee JH; Parker Institute for Cancer Immunotherapy at University of Pennsylvania; Philadelphia, PA, USA.
  • Chen Z; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Khan O; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Staupe RP; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Huang YJ; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Shi J; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Giles JR; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
  • Wherry EJ; Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, USA.
bioRxiv ; 2023 Apr 17.
Article in En | MEDLINE | ID: mdl-37131713

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: United States