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A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.
Bamezai, Shiva; Pulikkottil, Alex Jose; Yadav, Tribhuwan; Vegi, Naidu M; Mueller, Julia; Mark, Jasmin; Mandal, Tamoghna; Feder, Kristin; Ihme, Susann; Song, Chenlin; Rosler, Reinhild; Wiese, Sebastian; Hoell, Jessica I; Kloetgen, Andreas; Karsan, Aly; Kumari, Ankita; Wojenski, Luke; Sinha, Amit U; Gonzalez-Menendez, Irene; Quintanilla-Martinez, Leticia; Donato, Elisa; Trumpp, Andreas; Kruse, Elisabeth; Hamperl, Stephan; Zou, Lee; Rawat, Vijay P S; Buske, Christian.
Affiliation
  • Bamezai S; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Pulikkottil AJ; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Yadav T; Department of Pathology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA.
  • Vegi NM; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Mueller J; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Mark J; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Mandal T; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Feder K; Department of Oncology Pathology, Karolinska Institute, Stockholm, Sweden.
  • Ihme S; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Song C; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
  • Rosler R; Division of Molecular Biology of the Cell II, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany.
  • Wiese S; Core Unit Mass Spectrometry and Proteomics, Faculty of Natural Science, Ulm University, Ulm, Germany.
  • Hoell JI; Core Unit Mass Spectrometry and Proteomics, Faculty of Natural Science, Ulm University, Ulm, Germany.
  • Kloetgen A; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine Universität Düsseldorf, Düsseldorf, Germany.
  • Karsan A; Department of Pediatric Hematology and Oncology, Martin Luther University Halle-Wittenberg, Halle, Germany.
  • Kumari A; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine Universität Düsseldorf, Düsseldorf, Germany.
  • Wojenski L; Department of Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Sinha AU; Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada.
  • Gonzalez-Menendez I; Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada.
  • Quintanilla-Martinez L; Basepair Technology Inc, New York, NY.
  • Donato E; Basepair Technology Inc, New York, NY.
  • Trumpp A; Basepair Technology Inc, New York, NY.
  • Kruse E; Institute of Pathology and Neuropathology, Eberhard Karls University of Tübingen and Comprehensive Cancer Center, University Hospital Tübingen, Tübingen, Germany.
  • Hamperl S; Cluster of Excellence iFIT (EXC 2180), Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany.
  • Zou L; Institute of Pathology and Neuropathology, Eberhard Karls University of Tübingen and Comprehensive Cancer Center, University Hospital Tübingen, Tübingen, Germany.
  • Rawat VPS; Cluster of Excellence iFIT (EXC 2180), Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany.
  • Buske C; HI-STEM-Heidelberg Institute for Stem Cell Technology and Experimental Medicine gGmbH, Heidelberg, Germany.
Blood ; 142(1): 90-105, 2023 07 06.
Article in En | MEDLINE | ID: mdl-37146239
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute Limits: Humans Language: En Journal: Blood Year: 2023 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute Limits: Humans Language: En Journal: Blood Year: 2023 Type: Article Affiliation country: Germany