Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway.

Ouyang, Lingyi; He, Tao; Xing, Yiqiao

Ouyang, Lingyi; He, Tao; Xing, Yiqiao.

Affiliation

Ouyang L; Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei, China.
He T; Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei, China.
Xing Y; Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei, China. yiqiao_xing57@whu.edu.cn.

Graefes Arch Clin Exp Ophthalmol ; 261(12): 3489-3502, 2023 Dec.

Article in En | MEDLINE | ID: mdl-37199801

Subject(s)

Optic Nerve Injuries; Retinal Ganglion Cells; Animals; Male; Mice; Disease Models, Animal; Kelch-Like ECH-Associated Protein 1/metabolism; Mice, Inbred C57BL; Nerve Crush; NF-E2-Related Factor 2/genetics; NF-E2-Related Factor 2/metabolism; NF-E2-Related Factor 2/pharmacology; Optic Nerve/metabolism; RNA, Small Interfering/metabolism; RNA, Small Interfering/pharmacology; Signal Transduction

Key words

Neuroprotection; Optic nerve crush; Park7; Retinal ganglion cell

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Ganglion Cells / Optic Nerve Injuries Limits: Animals Language: En Journal: Graefes Arch Clin Exp Ophthalmol Year: 2023 Type: Article Affiliation country: China

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