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Lipidated variants of the antimicrobial peptide nisin produced via incorporation of methionine analogs for click chemistry show improved bioactivity.
Guo, Longcheng; Wang, Chenhui; Broos, Jaap; Kuipers, Oscar P.
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  • Guo L; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.
  • Wang C; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.
  • Broos J; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.
  • Kuipers OP; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands. Electronic address: o.p.kuipers@rug.nl.
J Biol Chem ; 299(7): 104845, 2023 07.
Article in En | MEDLINE | ID: mdl-37209826
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lactococcus lactis / Click Chemistry / Methionine / Nisin Language: En Journal: J Biol Chem Year: 2023 Type: Article Affiliation country: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lactococcus lactis / Click Chemistry / Methionine / Nisin Language: En Journal: J Biol Chem Year: 2023 Type: Article Affiliation country: Netherlands