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High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro.
Soldati, Sasha; Bär, Alexander; Vladymyrov, Mykhailo; Glavin, Dale; McGrath, James L; Gosselet, Fabien; Nishihara, Hideaki; Goelz, Susan; Engelhardt, Britta.
Affiliation
  • Soldati S; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
  • Bär A; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
  • Vladymyrov M; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
  • Glavin D; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
  • McGrath JL; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
  • Gosselet F; Blood-Brain Barrier Laboratory, University of Artois, Lens, France.
  • Nishihara H; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
  • Goelz S; Department of Neurotherapeutics, Yamaguchi University, Yamaguchi, Japan.
  • Engelhardt B; Biogen, Cambridge, MA, USA.
J Neuroinflammation ; 20(1): 123, 2023 May 23.
Article in En | MEDLINE | ID: mdl-37221552
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / T-Lymphocytes Limits: Humans Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2023 Type: Article Affiliation country: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / T-Lymphocytes Limits: Humans Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2023 Type: Article Affiliation country: Switzerland