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Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function.
Landim-Vieira, Maicon; Ma, Weikang; Song, Taejeong; Rastegarpouyani, Hosna; Gong, Henry; Coscarella, Isabella Leite; Bogaards, Sylvia J P; Conijn, Stefan P; Ottenheijm, Coen A C; Hwang, Hyun S; Papadaki, Maria; Knollmann, Bjorn C; Sadayappan, Sakthivel; Irving, Thomas C; Galkin, Vitold E; Chase, P Bryant; Pinto, Jose Renato.
Affiliation
  • Landim-Vieira M; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306.
  • Ma W; Department of Biology, Illinois Institute of Technology, Chicago, IL 60616.
  • Song T; Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267.
  • Rastegarpouyani H; Department of Biological Science, Florida State University, Tallahassee, FL 32306.
  • Gong H; Institude of Molecular Biophysics, Florida State University, Tallahassee, FL 32306.
  • Coscarella IL; Department of Biology, Illinois Institute of Technology, Chicago, IL 60616.
  • Bogaards SJP; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306.
  • Conijn SP; Department of Physiology, Amsterdam University Medical Center, Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
  • Ottenheijm CAC; Department of Physiology, Amsterdam University Medical Center, Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
  • Hwang HS; Department of Physiology, Amsterdam University Medical Center, Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
  • Papadaki M; Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL 32306.
  • Knollmann BC; Department of Cell and Molecular Physiology, Loyola University Chicago Stritch School of Medicine, Chicago, IL 60153.
  • Sadayappan S; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232.
  • Irving TC; Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267.
  • Galkin VE; Department of Biology, Illinois Institute of Technology, Chicago, IL 60616.
  • Chase PB; Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA 23507.
  • Pinto JR; Department of Biological Science, Florida State University, Tallahassee, FL 32306.
Proc Natl Acad Sci U S A ; 120(23): e2221244120, 2023 06 06.
Article in En | MEDLINE | ID: mdl-37252999
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Troponin T / Myofibrils Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Troponin T / Myofibrils Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article