Structural Model for Factor X Inhibition of IgM and Complement-Mediated Neutralization of Adenovirus.

Wagner, Nicole; Shayakhmetov, Dmitry M; Stewart, Phoebe L

Wagner, Nicole; Shayakhmetov, Dmitry M; Stewart, Phoebe L.

Affiliation

Wagner N; Cleveland Center for Membrane and Structural Biology, Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106, USA.
Shayakhmetov DM; Lowance Center for Human Immunology, Departments of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
Stewart PL; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.

Viruses ; 15(6)2023 06 09.

Article in En | MEDLINE | ID: mdl-37376642

Subject(s)

Adenoviridae; Adenoviruses, Human; Humans; Factor X/metabolism; Tissue Distribution; Complement System Proteins/metabolism; Adenoviruses, Human/genetics; Capsid Proteins/genetics; Immunoglobulin M; Models, Structural

Key words

adenovirus; complement C1; complement C3; complement C4; factor X; immunoglobulin M; molecular dynamics; neutralization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenoviridae / Adenoviruses, Human Type of study: Prognostic_studies Limits: Humans Language: En Journal: Viruses Year: 2023 Type: Article Affiliation country: United States

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