CRISPR-Cas9 screening identified lethal genes enriched in necroptosis pathway and of prognosis significance in osteosarcoma.

Cheng, Ling; Xiong, Wei; Li, Song; Wang, Gao; Zhou, Jie; Li, Haoguang

Cheng, Ling; Xiong, Wei; Li, Song; Wang, Gao; Zhou, Jie; Li, Haoguang.

Affiliation

Cheng L; Department of Rehabilitation Medicine, Nanchang Hongdu Hospital of TCM, Nanchang, China.
Xiong W; Department of Rehabilitation Medicine, Nanchang Hongdu Hospital of TCM, Nanchang, China.
Li S; Department of Rehabilitation Medicine, Nanchang Hongdu Hospital of TCM, Nanchang, China.
Wang G; Department of Rehabilitation Medicine, Nanchang Hongdu Hospital of TCM, Nanchang, China.
Zhou J; School of Medicine, Nanchang University, Nanchang, China.
Li H; School of Medicine, Nanchang University, Nanchang, China.

J Gene Med ; 25(12): e3563, 2023 Dec.

Article in En | MEDLINE | ID: mdl-37421290

Subject(s)

Bone Neoplasms; Osteosarcoma; Humans; Genes, Lethal; CRISPR-Cas Systems; Necroptosis/genetics; Osteosarcoma/diagnosis; Osteosarcoma/genetics; Bone Neoplasms/diagnosis; Bone Neoplasms/genetics

Key words

CERES analysis; CRISPR-Cas9; chemotherapy targets; osteosarcoma; weighted gene co-expression network analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: J Gene Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2023 Type: Article Affiliation country: China

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