Isolation and characterization of antibiotic X-14547A, a novel monocarboxylic acid ionophore produced by Streptomyces antibioticus NRRL 8167.
J Antibiot (Tokyo)
; 32(2): 100-7, 1979 Feb.
Article
in En
| MEDLINE
| ID: mdl-374323
ABSTRACT
A novel carboxylic acid ionophore, antibiotic X-14547A, closely related to the polyether antibiotics has been isolated along with four other metabolites from fermented cultures of a new strain of Streptomyces antibioticus. The structure, determined by X-ray analysis of the R(+)-1-amino-1-(4-bromophenyl)-ethane salt contained pyrrole carbonyl and trans-butadienyl chromophores in addition to the unusual tetrahydroindane bicyclic ring system. A second novel metabolite was identified as 3-ethyl-1,3-dihydro-3-methoxy-2H-indol-2-one.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ionophores
/
Anti-Bacterial Agents
Language:
En
Journal:
J Antibiot (Tokyo)
Year:
1979
Type:
Article