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De novo design of protein structure and function with RFdiffusion.
Watson, Joseph L; Juergens, David; Bennett, Nathaniel R; Trippe, Brian L; Yim, Jason; Eisenach, Helen E; Ahern, Woody; Borst, Andrew J; Ragotte, Robert J; Milles, Lukas F; Wicky, Basile I M; Hanikel, Nikita; Pellock, Samuel J; Courbet, Alexis; Sheffler, William; Wang, Jue; Venkatesh, Preetham; Sappington, Isaac; Torres, Susana Vázquez; Lauko, Anna; De Bortoli, Valentin; Mathieu, Emile; Ovchinnikov, Sergey; Barzilay, Regina; Jaakkola, Tommi S; DiMaio, Frank; Baek, Minkyung; Baker, David.
Affiliation
  • Watson JL; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Juergens D; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Bennett NR; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Trippe BL; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Yim J; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA.
  • Eisenach HE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Ahern W; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Borst AJ; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA.
  • Ragotte RJ; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Milles LF; Columbia University, Department of Statistics, New York, NY, USA.
  • Wicky BIM; Irving Institute for Cancer Dynamics, Columbia University, New York, NY, USA.
  • Hanikel N; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Pellock SJ; Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Courbet A; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Sheffler W; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Wang J; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Venkatesh P; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Sappington I; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.
  • Torres SV; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Lauko A; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • De Bortoli V; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Mathieu E; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Ovchinnikov S; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Barzilay R; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Jaakkola TS; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • DiMaio F; Institute for Protein Design, University of Washington, Seattle, WA, USA.
  • Baek M; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Baker D; Institute for Protein Design, University of Washington, Seattle, WA, USA.
Nature ; 620(7976): 1089-1100, 2023 Aug.
Article in En | MEDLINE | ID: mdl-37433327
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Deep Learning Type of study: Prognostic_studies Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Deep Learning Type of study: Prognostic_studies Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: United States