Dihydroartemisinin inhibits EMT of glioma via gene BASP1 in extrachromosomal DNA.

Que, Zhongyou; Zhou, Zhiwei; Liu, Sheng; Zheng, Wenhua; Lei, Bingxi

Que, Zhongyou; Zhou, Zhiwei; Liu, Sheng; Zheng, Wenhua; Lei, Bingxi.

Affiliation

Que Z; Department of Neurosurgery, Shenzhen Samii Medical Center, Shenzhen, China.
Zhou Z; Department of Neurosurgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China; Faculty of Health Sciences, University of Macau, Taipa, Macau, China.
Liu S; Department of Neurosurgery, Shenzhen Samii Medical Center, Shenzhen, China.
Zheng W; Faculty of Health Sciences, University of Macau, Taipa, Macau, China. Electronic address: wenhuazheng@um.edu.mo.
Lei B; Department of Neurosurgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Electronic address: leibingxi@mail.sysu.edu.cn.

Biochem Biophys Res Commun ; 675: 130-138, 2023 10 01.

Article in En | MEDLINE | ID: mdl-37473527

Subject(s)

Brain Neoplasms; DNA, B-Form; Glioma; Animals; Mice; Brain Neoplasms/drug therapy; Brain Neoplasms/genetics; Brain Neoplasms/metabolism; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Glioma/drug therapy; Glioma/genetics; Glioma/metabolism; Reactive Oxygen Species/metabolism; Humans

Key words

Dihydroartemisinin(DHA); Epithelial-mesenchymal transition (EMT); Extrachromosomal DNA(ecDNA); Glioblastoma(GBM)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / DNA, B-Form / Glioma Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2023 Type: Article Affiliation country: China

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