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Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer.
Li, Xiaoling; Wang, Yunguan; Deng, Su; Zhu, Guanghui; Wang, Choushi; Johnson, Nickolas A; Zhang, Zeda; Tirado, Carla Rodriguez; Xu, Yaru; Metang, Lauren A; Gonzalez, Julisa; Mukherji, Atreyi; Ye, Jianfeng; Yang, Yuqiu; Peng, Wei; Tang, Yitao; Hofstad, Mia; Xie, Zhiqun; Yoon, Heewon; Chen, Liping; Liu, Xihui; Chen, Sujun; Zhu, Hong; Strand, Douglas; Liang, Han; Raj, Ganesh; He, Housheng Hansen; Mendell, Joshua T; Li, Bo; Wang, Tao; Mu, Ping.
Affiliation
  • Li X; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Wang Y; Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Deng S; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Zhu G; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada.
  • Wang C; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Johnson NA; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Zhang Z; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Tirado CR; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Xu Y; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Metang LA; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Gonzalez J; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Mukherji A; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Ye J; Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, USA.
  • Yang Y; Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.
  • Peng W; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Tang Y; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, TX, USA.
  • Hofstad M; Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Xie Z; Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.
  • Yoon H; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Chen L; Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Liu X; Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA.
  • Chen S; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada.
  • Zhu H; Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.
  • Strand D; Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.
  • Liang H; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, TX, USA; Department of Systems Biology, MD Anderson Cancer Center, Houston, TX, USA.
  • Raj G; Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.
  • He HH; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada.
  • Mendell JT; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA; Hamon Center for Regenerative Science and Medicine, UT Southwestern
  • Li B; Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, USA.
  • Wang T; Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.
  • Mu P; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA; Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: p
Cancer Cell ; 41(8): 1427-1449.e12, 2023 08 14.
Article in En | MEDLINE | ID: mdl-37478850
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms Limits: Humans / Male Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms Limits: Humans / Male Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Type: Article Affiliation country: United States