Methionine sulfoxide reductases and cholesterol transporter STARD3 constitute an efficient system for detoxification of cholesterol hydroperoxides.

Lim, Jung Mi; Sabbasani, Venkata R; Swenson, Rolf E; Levine, Rodney L

Lim, Jung Mi; Sabbasani, Venkata R; Swenson, Rolf E; Levine, Rodney L.

Affiliation

Lim JM; Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. Electronic address: jungmi.lim@nih.gov.
Sabbasani VR; Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, Rockville, Maryland, USA.
Swenson RE; Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, Rockville, Maryland, USA.
Levine RL; Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.

J Biol Chem ; 299(9): 105099, 2023 09.

Article in En | MEDLINE | ID: mdl-37507014

Subject(s)

Cholesterol; Hydrogen Peroxide; Membrane Proteins; Methionine Sulfoxide Reductases; Cholesterol/analogs & derivatives; Cholesterol/metabolism; Hydrogen Peroxide/metabolism; Methionine/metabolism; Methionine Sulfoxide Reductases/genetics; Methionine Sulfoxide Reductases/metabolism; Oxidation-Reduction; Sulfoxides/metabolism; HEK293 Cells; HeLa Cells; Humans; Membrane Proteins/genetics; Membrane Proteins/metabolism; Endosomes/metabolism; Lysosomes/metabolism

Key words

STARD3; cholesterol; cholesterol hydroperoxide; lipid peroxidation; methionine; methionine sulfoxide reductase; oxidationreduction (redox); oxidative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Methionine Sulfoxide Reductases / Hydrogen Peroxide / Membrane Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2023 Type: Article

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