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Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir.
Hu, Yanmei; Lewandowski, Eric M; Tan, Haozhou; Zhang, Xiaoming; Morgan, Ryan T; Zhang, Xiujun; Jacobs, Lian M C; Butler, Shane G; Gongora, Maura V; Choy, John; Deng, Xufang; Chen, Yu; Wang, Jun.
Affiliation
  • Hu Y; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, New Brunswick, New Jersey 08854, United States.
  • Lewandowski EM; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.
  • Tan H; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, New Brunswick, New Jersey 08854, United States.
  • Zhang X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
  • Morgan RT; Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
  • Zhang X; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.
  • Jacobs LMC; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.
  • Butler SG; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.
  • Gongora MV; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.
  • Choy J; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.
  • Deng X; Department Biology, School of Arts and Sciences, the Catholic University of America, Washington, DC 20064, United States.
  • Chen Y; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
  • Wang J; Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
ACS Cent Sci ; 9(8): 1658-1669, 2023 Aug 23.
Article in En | MEDLINE | ID: mdl-37637734

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Cent Sci Year: 2023 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Cent Sci Year: 2023 Type: Article Affiliation country: United States