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Sorafenib induces cardiotoxicity through RBM20-mediated alternative splicing of sarcomeric and mitochondrial genes.
Liu, Songming; Yue, Shanshan; Guo, Yuxuan; Han, Jing-Yan; Wang, Huan.
Affiliation
  • Liu S; Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
  • Yue S; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing 100191, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing 100191, China.
  • Guo Y; Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, School of Basic Medical Sciences, Beijing 100191, China.
  • Han JY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing 100191, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing 100191, China. Electronic address: hanjingyan@bjmu.edu.cn.
  • Wang H; Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China. Electronic address: huan_sharon_
Pharmacol Res ; 198: 107017, 2023 Dec.
Article in En | MEDLINE | ID: mdl-38006979
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alternative Splicing / Cardiotoxicity Limits: Animals / Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alternative Splicing / Cardiotoxicity Limits: Animals / Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2023 Type: Article Affiliation country: China