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Bevacizumab in the Treatment of Refractory Brain Edema in High-grade Glioma.
Alsahlawi, Aysha K; Michaud-Couture, Claudie; Lachance, Alexandre; Bergeron-Gravel, Samuel; Létourneau, Mélanie; Bourget, Catherine; Gould, Peter V; Giannakouros, Panagiota; Nakada, Emily M; Faury, Damien; Crevier, Louis; Bouffet, Éric; Jabado, Nada; Larouche, Valérie; Renzi, Samuele.
Affiliation
  • Alsahlawi AK; Department of Neurological Surgery, McGill University, Montreal, Canada.
  • Michaud-Couture C; Faculty of Medicine, Université Laval, Quebec, Canada.
  • Lachance A; Faculty of Medicine, Université Laval, Quebec, Canada.
  • Bergeron-Gravel S; Division of Radiation Oncology, CHU de Québec - Université Laval, Quebec, Canada.
  • Létourneau M; Division of Radiation Oncology, CHU de Québec - Université Laval, Quebec, Canada.
  • Bourget C; Department of Diagnostic Radiology, CHU de Québec - Université Laval, Quebec, Canada.
  • Gould PV; Division of Molecular Biology, Medical Biochemistry and Pathology, CHU de Québec - Université Laval, Quebec, Canada.
  • Giannakouros P; Department of Pediatrics, Division of Hemato-Oncology, CHU de Québec-Université Laval, Quebec, Canada.
  • Nakada EM; Department of Pediatrics, McGill University, and The Research Institute of the McGill University Health Centre, Montreal, Canada.
  • Faury D; Department of Pediatrics, McGill University, and The Research Institute of the McGill University Health Centre, Montreal, Canada.
  • Crevier L; Division of Neurosurgery, Department of Surgery, CHU de Québec - Université Laval, Quebec, Canada.
  • Bouffet É; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Jabado N; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Larouche V; Department of Pediatrics, McGill University, and The Research Institute of the McGill University Health Centre, Montreal, Canada.
  • Renzi S; Department of Pediatrics, Division of Hemato-Oncology, CHU de Québec-Université Laval, Quebec, Canada.
J Pediatr Hematol Oncol ; 46(1): e87-e90, 2024 Jan 01.
Article in En | MEDLINE | ID: mdl-38032194
ABSTRACT
We report the case of a 14-year-old boy with a steroid-dependent refractory tumor whose longstanding dexamethasone treatment was successfully discontinued after a course of bevacizumab. The use of bevacizumab despite the absence of clear evidence of radionecrosis allowed a significant decrease in the amount of the brain edema.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Injuries / Brain Edema / Brain Neoplasms / Glioma Limits: Adolescent / Humans / Male Language: En Journal: J Pediatr Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2024 Type: Article Affiliation country: Canada
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Injuries / Brain Edema / Brain Neoplasms / Glioma Limits: Adolescent / Humans / Male Language: En Journal: J Pediatr Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2024 Type: Article Affiliation country: Canada