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Mpox and Chickenpox Coinfection: Case Series From Southern Nigeria.
Mmerem, Juliet I; Umenzekwe, Chukwudi C; Johnson, Simon M; Onukak, Asukwo E; Chika-Igwenyi, Nneka M; Chukwu, Sunday K; Onyeaghala, Chizaram A; Ozougwu, Jideofor J; Alasia, Datonye; Ehiakhamen, Odianosen; Nwankwo, Henry M; Ezejiofor, Ogochukwu I; Unigwe, Uche S; Iroezindu, Michael O.
Affiliation
  • Mmerem JI; Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
  • Umenzekwe CC; Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
  • Johnson SM; Department of Internal Medicine, Federal University Teaching Hospital, Owerri, Imo State, Nigeria.
  • Onukak AE; Department of Internal Medicine, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria.
  • Chika-Igwenyi NM; Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.
  • Chukwu SK; Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.
  • Onyeaghala CA; Department of Internal Medicine, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Rivers State, Nigeria.
  • Ozougwu JJ; Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
  • Alasia D; Department of Internal Medicine, Federal University Teaching Hospital, Owerri, Imo State, Nigeria.
  • Ehiakhamen O; Department of Internal Medicine, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Rivers State, Nigeria.
  • Nwankwo HM; National Mpox Emergency Operating Centre, National Centre for Disease Control, Abuja, Nigeria.
  • Ezejiofor OI; Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
  • Unigwe US; Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
  • Iroezindu MO; Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
J Infect Dis ; 229(Supplement_2): S260-S264, 2024 Mar 26.
Article in En | MEDLINE | ID: mdl-38058122
BACKGROUND: We describe clinicoepidemiologic characteristics of mpox-chickenpox coinfection in Nigeria. METHODS: A retrospective cohort analysis was performed of confirmed mpox cases in Nigeria from January 2022 to March 2023. Mpox and chickenpox were confirmed by real-time polymerase chain reaction (RT-PCR). RESULTS: Of 94 (60.0%) suspected cases, 56 had confirmed mpox, of whom 16 (28.6%) had chickenpox coinfection. The median age of confirmed mpox cases was 29 years (interquartile range, 20-37 years), 24 were men (60.7%), 6 (10.7%) were bisexual, and 5 (8.9%) died. Mpox-chickenpox-coinfected patients had more complications than mpox-monoinfected cases (56.3% vs 22.5%, P = .015). CONCLUSIONS: The high frequency of mpox-chickenpox coinfection argues for accelerated access to mpox and chickenpox vaccines in Africa.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chickenpox / Mpox (monkeypox) / Coinfection Limits: Adult / Female / Humans / Male Country/Region as subject: Africa Language: En Journal: J Infect Dis Year: 2024 Type: Article Affiliation country: Nigeria
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chickenpox / Mpox (monkeypox) / Coinfection Limits: Adult / Female / Humans / Male Country/Region as subject: Africa Language: En Journal: J Infect Dis Year: 2024 Type: Article Affiliation country: Nigeria