Incorporating mutational heterogeneity to identify genes that are enriched for synonymous mutations in cancer.

Rao, Yiyun; Ahmed, Nabeel; Pritchard, Justin; O'Brien, Edward P

Rao, Yiyun; Ahmed, Nabeel; Pritchard, Justin; O'Brien, Edward P.

Affiliation

Rao Y; Huck Institute of the Life Sciences, Pennsylvania State University, University Park, State College, PA, 16802, USA.
Ahmed N; Huck Institute of the Life Sciences, Pennsylvania State University, University Park, State College, PA, 16802, USA.
Pritchard J; Moderna, Inc., Cambridge, USA.
O'Brien EP; Department of Biomedical Engineering, Pennsylvania State University, University Park, State College, PA, 16802, USA. jrp94@psu.edu.

BMC Bioinformatics ; 24(1): 462, 2023 Dec 07.

Article in En | MEDLINE | ID: mdl-38062391

Subject(s)

Neoplasms; Silent Mutation; Humans; Genome, Human; Mutation; Neoplasms/pathology; RNA, Messenger; Proto-Oncogene Proteins c-bcl-2; DNA Mutational Analysis

Key words

Cancer driver; MutSigCV; Synonymous mutations

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silent Mutation / Neoplasms Limits: Humans Language: En Journal: BMC Bioinformatics Journal subject: INFORMATICA MEDICA Year: 2023 Type: Article Affiliation country: United States

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