Antibody Binding Captures High Energy State of an Antigen: The Case of Nsp1 SARS-CoV-2 as Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry.

Kant, Ravi; Mishra, Nawneet; Gross, Michael L

Kant, Ravi; Mishra, Nawneet; Gross, Michael L.

Affiliation

Kant R; Department of Chemistry, Washington University, St. Louis, MO 63130, USA.
Mishra N; Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Gross ML; Department of Chemistry, Washington University, St. Louis, MO 63130, USA.

Int J Mol Sci ; 24(24)2023 Dec 11.

Article in En | MEDLINE | ID: mdl-38139170

Subject(s)

COVID-19; SARS-CoV-2; Humans; Deuterium/chemistry; Deuterium Exchange Measurement/methods; Mass Spectrometry/methods; Proteins

Key words

Nsp1; antibody capture of high energy antigen; epitope; hydrogendeuterium exchange; mass spectrometry; paratope

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Int J Mol Sci Year: 2023 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google